4-Amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1H-indol-2-yl)-1H-pyrrole-3-carbonitrile
نویسندگان
چکیده
The title compound, 4-amino-5-benzoyl-1-benzyl-2-(4,5,6,7-tetrahydro-1H-indol-2-yl)- 1H-pyrrole-3-carbonitrile, was synthesized for the first time in a 40% yield by reaction of N-benzyl-3-imino-5,6,7,8-tetrahydro-3H-pyrrolo[1,2-a]indol-1-amine and 1-chloroacetophenone K2CO3/MeCN system (reflux, 6 h). product characterized 1H-NMR, 13C-NMR, IR spectroscopy, elemental analysis.
منابع مشابه
1-(2-Hydroxyethyl)-3-[(2-hydroxyethyl)amino]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
There are four molecules in the asymmetric unit of the title compound, C(16)H(17)N(3)O(4), in which the dihedral angles between the indole ring system and maleimide ring are 4.5 (3), 8.3 (3), 8.4 (2) and 10.4 (2)°. In the crystal, mol-ecules are linked by numerous N-H⋯O and O-H⋯O hydrogen bonds, generating a three-dimensional network.
متن کامل5-Benzoyl-2-(1H-indol-3-yl)-4-(4-methylphenyl)-4,5-dihydrofuran-3-carbonitrile
The furan ring in the title compound, C(27)H(20)N(2)O(2), adopts a twisted conformation about the sp(3)-sp(3) bond. The mol-ecular structure is stabilized by an intra-molecular C-H⋯O inter-action which generates an S(6) ring motif. The crystal packing is stabilized by N-H⋯O and C-H⋯O inter-actions generating centrosymmetric R(2) (2)(18) and C(6) chain motifs, respectively. A weak C-H⋯π inter-ac...
متن کامل(±)-trans-5-Benzoyl-4-(3-bromophenyl)-2-(1H-indol-3-yl)-4,5-dihydrofuran-3-carbonitrile
The furan ring in the title compound, C(26)H(17)BrN(2)O(2), adopts a twisted envelope conformation. The mol-ecular structure is stabilized by an intra-molecular C-H⋯O inter-action which generates an S(6) ring motif. The crystal packing is stabilized by N-H⋯O and C-H⋯Br inter-actions, generating an R(2) (2)(16) ring motif and a C(12) linear chain motif, respectively. Weak C-H⋯π bonding is also o...
متن کامل(±)-trans-5-Benzoyl-2-(1H-indol-3-yl)-4-phenyl-4,5-dihydrofuran-3-carbonitrile
The furan ring in the title compound, C(26)H(18)N(2)O(2), is twisted about the C(H)-C(H) bond. The mol-ecular structure is stabilized by an intra-molecular C-H⋯O inter-action, which generates an S(6) ring motif. The presence of N-H⋯N hydrogen bonds leads to inversion dimers, which are stabilized in the crystal packing by C-H⋯O and C-H⋯π inter-actions, forming layers that stack along the a axis.
متن کامل1-Benzyl-2-(1H-indol-3-yl)-5-oxopyrrolidine-2-carbonitrile
In the title compound, C(20)H(17)N(3)O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent mol-ecules are connected into infinite chains via an N-H⋯O hydrogen bond.
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ژورنال
عنوان ژورنال: Molbank
سال: 2023
ISSN: ['1422-8599']
DOI: https://doi.org/10.3390/m1547